Malaria Tablets Mefloquine-Larium

Malaria Tablets Mefloquine-Larium

Lariam 250mg tablets when used in treating malaria

Lariam (lar-ee-um) is a medicine which is used in preventing malaria and treating malaria. Lariam contains mefloquine hydrochloride. It is supplied by Roche Products Limited.

Lariam is used to prevent or treat certain types of malaria. It works by killing the parasites that cause malaria. It is used to prevent malaria in people who are in areas where there is an increased risk of getting malaria.

Other information about Lariam:

  • if you vomit within an hour of taking Lariam seek medical advice

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Lariam is used to prevent or treat certain types of malaria. It works by killing the parasites that cause malaria. It is used to prevent malaria in people who are in areas where there is an increased risk of getting malaria.

Other information about Lariam:

  • this medicine is usually only used for a maximum of one year when used in the prevention of malaria

Do not share your medicine with other people. It may not be suitable for them and may harm them.

The pharmacy label on your medicine tells you how much medicine you should take. It also tells you how often you should take your medicine. This is the dose that you and your prescriber have agreed you should take. You should not change the dose of your medicine unless you are told to do so by your prescriber.

If you feel that the medicine is making you unwell or you do not think it is working, then talk to your prescriber.

Whether this medicine is suitable for you

Lariam is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

  • are allergic or sensitive to medicines similar to Lariam such as quinine
  • have been treated for malaria with quinine within the last 12 hours
  • have had a live vaccine within the last three days or are having a vaccination soon
  • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
  • have epilepsy
  • have galactose intolerance
  • have glucose-galactose malabsorption problems
  • have heart problems
  • have kidney problems
  • have Lapp lactase deficiency

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for an infant who is under the age of 3 months or for an infant who weighs less than 5kg.

Over time it is possible that Lariam can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Lariam has become unsuitable, it is important that the prescriber is contacted immediately.

Lariam is not suitable for everyone and some people should never use it. Other people should only use it with special care. It is important that the person prescribing this medicine knows your full medical history.

Your prescriber may only prescribe this medicine with special care or may not prescribe it at all if you:

  • are allergic or sensitive to medicines similar to Lariam such as quinine
  • have had a live vaccine within the last three days or are having a vaccination soon
  • have or have had psychiatric problems such as depression
  • are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
  • have epilepsy
  • have galactose intolerance
  • have glucose-galactose malabsorption problems
  • have had convulsions
  • have heart problems
  • have kidney problems
  • have Lapp lactase deficiency
  • have liver problems

Furthermore the prescriber may only prescribe this medicine with special care or may not prescribe it at all for an infant who is under the age of 3 months or for an infant who weighs less than 5kg.

Over time it is possible that Lariam can become unsuitable for some people, or they may become unsuitable for it. If at any time it appears that Lariam has become unsuitable, it is important that the prescriber is contacted immediately.

Taking other medicines

Information specific to:

Lariam 250mg tablets when used in preventing malaria

Lariam 250mg tablets when used in treating malaria

If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.

The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.

Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.

The following medicines may interact with Lariam:

  • carbamazepine
  • chloroquine
  • halofantrine
  • ketoconazole
  • phenobarbital
  • phenytoin
  • quinidine
  • quinine
  • rifampicin
  • valproic acid

The following types of medicine may interact with Lariam:

  • medicines that affect electrical activity in the heart
  • medicines that are similar to Lariam
  • p-glycoprotein substrates
  • antiarrhythmics
  • anticoagulants
  • anticonvulsants
  • antidiabetics
  • antihistamines
  • beta-adrenergic blockers
  • calcium channel blockers
  • cytochrome P450 enzyme inducers
  • cytochrome P450 enzyme inhibitors
  • live vaccines
  • phenothiazines
  • tricyclic antidepressants

If you are taking Lariam and one of the above medicines or types of medicines, make sure your prescriber knows about it.

Family planning and pregnancy

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Lariam:

  • you should only take this medicine during pregnancy if your doctor thinks that you need it
  • if you could become pregnant, you must use effective contraception or abstain from penetrative sex while you are taking Lariam and for three months after you have stopped taking it. You must contact your prescriber if you become pregnant, or think you have become pregnant, during this time

You need to discuss your specific circumstances with your doctor to weigh up the overall risks and benefits of taking this medicine. You and your doctor can make a decision about whether you are going to take this medicine during pregnancy.

If the decision is that you should not have Lariam, then you should discuss whether there is an alternative medicine that you could take during pregnancy.

Information specific to:

Lariam 250mg tablets when used in preventing malaria

Most medicines, in some way, can affect the development of a baby in the womb. The effect on the baby differs between medicines and also depends on the stage of pregnancy that you have reached when you take the medicine.

In the case of Lariam:

  • you must not take Lariam during pregnancy. If you could become pregnant, you must use effective contraception or abstain from penetrative sex while you are taking Lariam and for three months after you have stopped taking it. You must contact your prescriber if you become pregnant, or think you have become pregnant, during this time
  • you should only take this medicine during pregnancy if your doctor thinks that you need it

This medicine is not suitable during pregnancy. It is very important that you seek urgent medical advice if you become pregnant or think you have become pregnant while taking this medicine.

If you are planning to become pregnant, you should discuss your personal circumstances with your doctor so that together you can make a decision about what treatment you may need during your pregnancy

Ingredients of your medicine

Medicines contain active ingredients. They may also contain other, additional ingredients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicine’s taste and appearance and to make it easier to take. Some may be used to prolong the life of the medicine.

You should check that you are able to take the ingredients in your medicine, especially if you have any allergies.

Lariam contains:

  • ammonium-calcium alginate
  • poloxamer (polyoxyethylene-polyoxypropylene copolymer)
  • crospovidone
  • lactose
  • magnesium stearate
  • maize starch
  • mefloquine hydrochloride
  • microcrystalline cellulose
  • talc

If you are not able to take any of the ingredients in your medicine, talk to your prescriber or pharmacist to see if they can suggest an alternative medicine. If you have reacted badly to Lariam before, do not take Lariam. Talk to your prescriber, pharmacist or nurse as soon as possible.

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